116 million adults in the US—more than the number affected by heart disease, diabetes, and cancer combined—live with common chronic pain conditions.  Of those individuals, 20-50% experience comorbid depression in parallel to their chronic pain, and are 2-3x more susceptible to suicidal ideation and behaviors.

Over the last 3 years, we’ve conducted extensive research specifically around the relationships between chronic pain and comorbid anxiety and depression, and more importantly, how organizations like yours can reduce the associated downstream effects of chronic pain including absenteeism and high medical claim costs.  

What is chronic pain?

Chronic pain is a long-term, debilitating health concern that affects physical, psychological, cognitive, and social functioning, resulting in downstream medical claim costs for organizations. Chronic pain conditions are associated with comorbid depression, anxiety, sleep disturbances, fatigue, neurocognitive changes, and the list goes on.

There is an estimated $560B-$635B annual total healthcare cost of chronic pain in the United States, and employee absenteeism is a well-documented cost of chronic pain.

Your employees struggling with chronic pain have issues with typical day-to-day demands and activities, unable to focus on anything other than their pain, and frequently struggle with productivity and absenteeism. Individuals experiencing pain-related depression and anxiety are also likely to have worse outcomes from chronic pain. Undiagnosed and untreated chronic pain forces employees to push aside their symptoms and continue work, return to work prematurely or take sick leave stemming from stress, physical demands, and job dissatisfaction.

Efficacy of Pain Management with AI Digital Interventions

The first study that Wysa conducted—a pain management study—aimed to examine the differences in engagement and effectiveness of leveraging an isolated AI (artificial intelligence) digital mental health intervention for users experiencing chronic pain.

Some background knowledge of the pain management study:

1. There were 51 US adults with self-reported chronic pain and co-existing elevated symptoms of anxiety and/or depression that were analyzed.
2. The study was over the course of an 8-week Wysa App for Chronic Pain program and acted as the only mental health resource throughout the study.
3. Individuals had access to Wysa’s conversational AI tool without the guided support of human coaches.

The results of the pain management study

The results point to AI digital Intervention as an effective, scalable solution for organizations.  We found clinically meaningful improvements in pain interference, physical function, and levels of anxiety and depression. Users engaged in a mean of 4.0 sessions per week, and a cumulative mean of 33.3 sessions during the eight-week study period.

What does this mean for your organization?

Knowing that conversational AI via an app can provide truly impactful mental healthcare to individuals struggling with chronic pain and comorbid anxiety and/or depression symptoms, AI digital interventions are the answer to scalable care. In addition, a mental health app can make a larger impact on absenteeism and medical claim cost savings.

Importance of establishing a therapeutic alliance with digital interventions

While mental health technology is scalable and effective when used as recommended, low engagement prevents digital interventions from having their intended reach and impact.  In a previous digital intervention study, participants disengaged within week 1 with average retention periods of 4-16 days. These numbers don’t evoke change.

A therapeutic alliance - described below - is one of the most robust mechanisms of change in psychotherapy interventions. Knowing that AI digital intervention has the ability to make a sizeable impact on the physical, mental, and social health of individuals who struggle with chronic pain, why do we see historically low adherence and engagement rates? The answer is simple. There is a lack of therapeutic alliance between the patient and the provider.

What is a therapeutic alliance?

A therapeutic alliance is measurable by the level of collaboration between the patient and provider on the task and goals of the course of treatment. If you don’t feel heard or understood by your provider, why would you feel inclined to return?

Establishing a therapeutic alliance with AI

If there is a lack of engagement, there will likely be low adherence to interventions and high dropout rates. Top-performing health apps have an average 30-day retention rate of only 15%. People with chronic pain are 2x as likely to drop out from self-guided digital interventions when compared to traditional, guided interventions.

The second Wysa study was on therapeutic alliance between a patient and provider using AI.  The purpose was to examine user retention and engagement with Wysa for Chronic Pain—a digital conversational agent based on Cognitive Behavioral Therapy (CBT) principles—that is designed to improve general well-being among people with chronic pain. CBT is form of psychological treatment for a wide range of mental health symptoms and conditions.

Some background knowledge about the therapeutic alliance study:

1. There were 51 adults with chronic musculoskeletal pain and who endorsed coexisting symptoms of depression or anxiety (score of ≥55 for depression or anxiety).
2. The study was over the course of an 8-week subscription to Wysa for Chronic Pain.
3. The study outcomes were user retention, defined as revisiting the app each week and on the last day of engagement, and user engagement, defined by the number of sessions the user completed.

The results of the therapeutic alliance study

AI-driven mental health conversational agents are a proven method in helping patients with chronic pain learn to self-manage their pain and deal with comorbidities like depression and anxiety.

50% of users in a Wysa digital intervention study continued returning to the app each week, and the median user retention period was 51 days. The study has successfully proven the ability to achieve high retention and engagement with a mental health app that uses digital AI and established behavioral paradigms, specifically to deliver CBT to people with mental health concerns and coexisting chronic pain.

Exhibit

Real-life example of 24/7, scalable mental health for global employees

Here’s a great example of how scalability and AI that successfully builds therapeutic alliance worked in tandem to improve the mental well-being of a company workforce, for employees within the US, and globally.

Post-pandemic life has sparked serious, record-breaking anxiety and depression levels within our workforce and the broader nation. Higher than ever before in history. Employees are looking to employers to offer mental health support for themselves and their families to promote sustainable and healthy lifestyles inside and outside of work. 

Wysa Clinical Development and Research